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Thread: Substrates for Drug-metabolizing Enzymes Exhibiting Genetic Variability

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    PharmD Year 1 TomHsiung's Avatar
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    Default Substrates for Drug-metabolizing Enzymes Exhibiting Genetic Variability

    Substrates for Drug-metabolizing Enzymes Exhibiting Genetic Variability

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    B.S. Pharm, West China School of Pharmacy, Class of 2007, Health System Pharmacist, RPh. Hematology, Infectious Disease.

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    PharmD Year 1 TomHsiung's Avatar
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    Also there are polymorphism of CYP2A6 and CYP3A4/5.

    CYP2A6 polymorphism lies in management of tobacco abuse. Nonsmokers are more likely to carry the defective CYP2A6 allele than are smokers. Besides, smokers who had the defective CYP2A6 allele smoked fewer cigarettes and are more likely to quit.
    B.S. Pharm, West China School of Pharmacy, Class of 2007, Health System Pharmacist, RPh. Hematology, Infectious Disease.

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